Here is a new video-insight by Professor Marco E. Bianchi, Co-founder and Part-owner of HMGBiotech. These video-insights offer concise, focused segments from Prof. Bianchi’s lecture, each exploring a specific aspect of HMGB1 biology.
14th video: Proposed model
Necrosis releases reduced HMGB1 to recruit leukocytes; oxidation generates disulfide-HMGB1, driving TLR4-mediated inflammation, while further ROS oxidation inactivates HMGB1 and promotes resolution.
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