Even after 20 Years, HMGB1 continues to surprise us. A groundbreaking international study has unveile
d a critical new role for HMGB1 that could redefine how we think about the biology of aging. Blood protein HMGB1 could be spreading aging throughout the body, acting as a systemic messenger of senescence.
ReHMGB1, a blood-borne driver of systemic aging revealed: HMGB1 never ages! Read More »
June marks Alzheimer’s & Brain Awareness Month, an important opportunity to advance dialogue on the molecular underpinnings of neurodegeneration.
In 2025 we celebrate HMGBiotech 20th anniversary, reaffirming our commitment towards innovation and dedication to advancing biomedical research.
20 years of excellence in HMGB1 research: celebrate with us! Read More »
2025 marks the 20th anniversary of HMGBiotech — a milestone that reflects two decades of innovation, collaboration, and dedication to advancing biomedical research.
Researches on High Mobility Group Box 1 (HMGB1) focus on its mediator role in fibrotic disease, and recent findings shed light on HMGB1 critical role in epithelial-mesenchymal transition (EMT) and pulmonary fibrosis associated with silicosis.
HMGB1 drives epithelial-mesenchymal transition and Fibrosis in Silicosi Read More »
As we mark World Autoimmune Arthritis Day, occurring on 20th May, it is critical to highlight the molecular underpinnings that drive chronic pain and inflammation in autoimmune joint diseases such as rheumatoid arthritis (RA).
HMGB1 and Autoimmune Arthritis: new frontiers in pain and inflammation management Read More »
HMGB1 release is a hallmark of pyroptosis, distinguishing it from non-inflammatory death pathways. Once released, HMGB1 binds to receptors like RAGE and TLR4.
HMGB1 and Pyroptosis: a molecular axis in Lung Cancer Immunopathology Read More »
At HMGBiotech, we offer an integrated Custom Protein Production & Engineering service tailored to the evolving needs of academic researchers, biotech startups, and pharmaceutical developers.
Custom protein production & engineering service Read More »
A particularly innovative aspect of the study involved investigating the role of extracellular HMGB1 in dendritic cell-mediated T cell polarization.
HMGB1 and immune regulation in intestinal inflammation (IBD) Read More »
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