HMGB1 has been shown to play a key role in Parkinson’s disease pathogenesis. Research and studies targeting High Mobility Group Box 1 (HMGB1) protein in Parkinson’s disease (PD) has recently emerged, with promising results in the inhibition of HMGB1.
HMGBiotech specializes in the production of LPS-free proteins. LPS (Bacterial endotoxin lipopolysaccharide) is a powerful inducer of the immune system and can introduce undesirable variables and limitations in certain experimental setups.
HMGBiotech Srl has taken part to a study, published in June, in which are discovered CXCL12 as the first fuzzy chemokines heterocomplex reported so far and the unexpected role of the acidic intrinsically disordered region (IDR), in HMGB1●CXCL12 heterocomplex formation.
On 28th June, Dr Andrea Lamarca, researcher in HMGBiotech lab, will give a speech at IMIG2023, the International Mesothelioma Interest Group conference.
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