World Mental Health Day, occurring on the 10th of October, recalls to us the importance of researches linking inflammation and mental health disorders, in particular major depressive disorder (MDD).
HMGB1 and new frontiers in mental health research Read More »
LPS-free HMGB1 proteins allow for safe and accurate in vitro and in vivo researches, in order to go deeper in heart-related diseases.
Cardiovascular research involving HMGB1 LPS-Free proteins Read More »
A recent research, published two weekes ago, shows that nuclear HMGB1 is essential for the anti-tumor activity of CD8 T cells, particularly in enhancing interferon gamma (IFN-γ) production, a key cytokine in tumor elimination.
Nuclear HMGB1 and anti-tumor immunity Read More »
Emerging research highlights the relevant role of High-Mobility Group Box 1 (HMGB1) in muscular diseases, offering new insights that could inform future therapeutic strategies for SMA.
Spinal Muscular Atrophy and HMGB1 protein Read More »
A recent study has highlighted the significant role of the disulfide form of HMGB1 in liver pathologies related to excessive alcohol consumption.
The role of HMGB1 disulfide form in alcohol-associated liver diseases Read More »
HMGB1 protein plays significant roles in conditions such as liver ischemia-reperfusion (LI/R) injury and Hepatitis B virus (HBV) infection.
World Hepatitis Day: Focusing on HMGB1 in Liver Health Read More »
Recent studies have provide significant insights into the role of High Mobility Group Box 1 (HMGB1) in Alzheimer’s disease (AD), particularly its involvement in neuroinflammation and cognitive decline.
Alzheimer’s Disease Pathogenesis and HMGB1 protein Read More »
Studies have highlighted the significant role of High-Mobility Group Box 1 (HMGB1) in AD, providing new insights and potential therapeutic applications.
HMGB1 as a target in Alzheimer’s Disease Research Read More »
A study just published on ASCO’s Journal of Clinical Oncology focuses on how lung metastasis remains a significant challenge in treating Triple Negative Breast Cancer (TNBC).
Exosomal HMGB1 in Lung-Tropic Metastasis of Triple Negative Breast Cancer Read More »
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