Here is a new video-insight by Professor Marco E. Bianchi, Co-founder and Part-owner of HMGBiotech. These video-insights offer concise, focused segments from Prof. Bianchi’s lecture, each exploring a specific aspect of HMGB1 biology.
8th video: HMGB1 is released both passively and actively
HMGB1 can be released either passively from dead cells or actively from living cells through an NF-κB and interferon–dependent mechanism involving STAT-mediated acetylation, which allows its nuclear export and lysosomal secretion without immediate new protein synthesis.
Explore our website to access scientific resources, vist our shop, and stay updated on the latest developments in the HMGB1 field.
