Among others, HMGB1 protein has been identified for its significant role in the pathology of autism and neurological conditions.
Unraveling Autism’s complexities through Epigenetics and Neuroimmunology Read More »
A relevant research concerning a wider perspective on protective immunity has just been published: Maura Casalgrandi, researcher in HMGBiotech, is one of the authors involved in the study.
Recent insights reveal HMGB1’s central function in regulating the interplay between autophagy and apoptosis, processes essential for maintaining cellular homeostasis and determining the fate of cancer cells.
Recent findings illuminate a crucial pathway from fatty liver disease to hepatocellular carcinoma (HCC), where High Mobility Group Box 1 (HMGB1) emerges as a crucial player in the progression of liver diseases.
As we commemorate World Cancer Day, it’s crucial to spotlight groundbreaking researches that drive our path to discovery cancer mechanism.
The dual role of HMGB1 in Cancer Immunity and its potential in immunotherapy Read More »
The quest to accurately quantify High Mobility Group Box 1 (HMGB1) and its redox variants in human plasma has been a challenging endeavor in biomedical research, due to the complexities presented by interference from other proteins and autoantibodies.
Since its discovery, 50 years ago, the role of HMGB1 protein has shift from mere structural protein in chromatin, to be considered as a key factor in new therapeutic approaches to diseases, such as intracranial aneurysms.
Highlighting HMGB1’s Role in Intracranial Aneurysms Read More »
To celebrate the 50th anniversary of the discovery of High Mobility Group Box 1 (HMGB1), it is important to underline its multifaceted roles in cellular biology and disease pathology.
Celebrating 50 years of HMGB1: From Chromatin to Therapy Read More »
A recent research showed High Mobility Group Box Protein 1 (HMGB1) as a promising biomarker in early sepsis recognition.
HMGB1: a key biomarker in early Sepsis recognition Read More »
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